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doc. dr. Rasa Žūkienė

Rasa Žūkienė



The effect of hyperthermia on mitochondrial oxidative phosphorylation system, cell and tissue viability, applications of HPLC and spectral analysis methods in metabolomics and proteomics

Membership of professional associations

Since 1999 – member of Lithuanian Biochemical Society (member of Federation of European Biochemical Society)

Since 2010 – council member of Lithuanian Biochemical Society (member of Federation of European Biochemical Society)


  • 2010-2011 Researcher, project “The effect of hyperthermia on liver mitochondria: the dependence on gender and age” (supported by the Research Council of Lithuania).
  • 2007-2009 Researcher, project “Investigation of biological response to thermal impact and computational modeling“ (supported by the Lithuanian State Science and Studies Foundation).
  • Researcher, project „Development of the models to regenerate heart structures employing stem cells, specialized cells and biological tissues“ (supported by the Lithuanian State Science and Studies Foundation).
  • 2006 Researcher, project “The reasons of the sensitivity of tumour cells to hyperthermia: the role of mitochondrial permeability transition pore“ (supported by the Lithuanian State Science and Studies Foundation).



  1. Naučienė Z, Žūkienė R, Degutytė-Fomins L, Mildažienė V. Mitochondrial membrane barrier function as a target of hyperthermia. Medicina. 2012, 48(5), 249-255.
  2. Zukiene R, Nauciene Z, Ciapaite J, Mildaziene V. Acute temperature resistance threshold in heart mitochondria: febrile temperature activates function but exceeding it collapses the membrane barrier. Int J Hyperthermia. 2010, 26(1), 56-66.
  3. Minet O, Dressler C, Beuthan J, Zabaryło U, Žūkienė R, Mildažienė V. Fluorescence Imaging of Calcium Loading and Mitochondrial Depolarization in Cancer Cells Exposed to Heat Stress. C.D. Geddes (ed.), Reviews in Fluorescence 2008. 2010, Springer Science+Business Media, LLC, 89-118.
  1. Naučienė Z; Mildažienė V; Vieželienė D; Žūkienė R. Biochemijos laboratoriniai darbai : mokymo priemonė biologijos bei aplinkotyros ir ekologijos bakalauro studijų programų studentams [textbook, electronic resource]. Kaunas : Vytauto Didžiojo universiteto leidykla, 2010. 84 p. ISBN 9789955125761. http://vddb.laba.lt/obj/LT-eLABa-0001:B.03~2010~ISBN_978-9955-12-576-1.
  2. Žūkienė R, Naučienė Z, Degutytė-Fomins L, Mildažienė V. Gender-dependence of hyperthermia induced changes in respiration of rat liver mitochondria. Biologija. 2010, 56(1–4), 88–92.
  3. Degutytė-Fomins L, Žūkienė R, Buzaitė O, Dzikas P, Naučienė Z, Mildažienė V. Differentiation-related changes in myogenic stem cells. Biologija. 2010, 56(1–4), 55–62.
  4. Degutytė-Fomins L, Žūkienė R, Maijorovaitė Ž, Naučienė Z, Mildažienė V. Differential scanning calorimetry (DSC) analysis of isolated liver and heart mitochondria. Biologija. 2008, 3, 167-170.
  5. Antanavičiūtė I., Naučienė Z., Buzaitė O., Žūkienė R. Effect of temperature and mechanical stress on rabbit skeletal myoblasts viability and concentrations of adenine and pyridine nucleotides. Lithuanian Journal of Cardiology. 2008, 15(1), 76-82.
  6. Žūkienė R., Naučienė Z., Čiapaitė J., Mildažienė V. Response of heart mitochondria to hyperthermia: activation at the febrile temperature versus loss of the inner membrane barrier at higher temperatures. Biologija. 2007, 53(4), 34-39.


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