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General Genetic (BIO3005)

Course code

Course group

Volume in ECTS credits

Course hours

BIO 3005

C

6

160

Course type (compulsory or optional)

Compulsory

Course level (study cycle)

Bachelor

Semester the course is delivered

Spring

Study form (face-to-face or distant)

Face-to-face

Course title in Lithuanian

BENDROJI GENETIKA

Course title in English

GENERAL GENETICS

Short course annotation in Lithuanian

Dalyko tikslas yra suvokti paveldimumo ir kintamumo reikšmę gyvojo pasaulio evoliucijoje. Šio dalyko dėstymas pradedamas analizuojant gametų segregacijos ir paveldimumo principus, palaipsniui pereinama prie suvokimo, kaip ir kokios genų sąveikos lemia gyvų organizmų požymių kaitą gamtoje. Pirmoje kurso dalyje didžiausias dėmesys skiriamas klasikinei (Mendelinei) genetikai, tuo tarpu likusioje kurso dalyje pateikiami ir šiuolaikiniai atradimai  molekulinės biologijos srityje, bei jų taikymas šiandieniniame pasaulyje.

Short course annotation in English

The aim of this course is to study the principles and major concepts in organisms’ heredity and variability. This course starts from analyzing the principles of mendelian segregation and heredity, and then goes to understanding of genes interactions and the origin of variability of traits in nature. The first half of the course will focus on the basic principles of classical (Mendelian) genetics, while the second half of the course will deal with the modern discoveries of molecular biology and their applications in today's world.

Prerequisites for entering the course

Basic biology, General Biochemistry 1.

Course aim

The aim of the course is to provide an introduction to high-level programming for students who are assumed to have no prior programming experience.

Content (topics)

 1. Overview of Genetics; Mendelian Inheritance.
 2. Relationship between Genes and Expression of Traits
 3. Reproduction and Chromosome Transmission; Chromosome Organization and Molecular Structure of DNA and RNA.
 4. Linkage and Genetic Mapping in Prokaryotes and Eukaryotes.
 5. Genetic Transfer: DNA Replication, Gene Transcription and RNA Modification, Translation of mRNA.
 6. Gene Regulation in Prokaryotes and Eukaryotes, Recombination and Transposition at the Molecular Level.
 7. Cytogenetics.
 8. Variation in Chromosome Structure and Number
 9. Non-Mendelian Inheritance.
 10. Gene Mutation and DNA Repair.
 11. Quantitative Genetics, Developmental Genetics
 12. Medical Genetics; Cancer and Gene Therapy.
 13. Recombinant DNA Technology,.
 14. Structural and Functional Genomics, Proteomics.

Practical work (contents):

Variables and arithmetic calculations; manipulating on inputs-outputs; loops and control structures; handling the text file data; working with one-dimensional and two-dimensional arrays: searching, deleting, inserting, replacing, sorting and interchange of the elements.

Distribution of workload for students (contact and independent work hours)

Lectures – 45 hours, laboratory work – 30 hours,  individual work – 85 hours.

Structure of cumulative score and value of its constituent parts

Final assessment sums the assessments of written final examination (50%), written mid-term examination (17%) and assessment of laboratory works (33%).

Recommended reference materials

No.

 

Publication year

Authors of publication and title

Publishing house

Number of copies in

University library

Self-study rooms

Other libraries 

Basic materials

1.

2007

Lamb, Bernard C. The applied genetics of humans, animals, plants and fungi /

London : Imperial College Press

1

1

 

2.

2000

Rančelis V. Genetika.

Vilnius: Akademija

66

5

 

3.

2008

Rančelis V.Augalų genetika.

Kaunas-Technologhija

10

2

 

4.

2003

Paulauskas A., G. Slapšytė, V. Morkūnas. Bendrosios genetikos tyrimų metodai ir pratybos

Vilnius: UAB "Inforastras

50

10

 

Supplementary materials

1.

2004

Brooker, Robert J. Genetics: Analysis & Principles

 

1.

2001

Kučinskas V. Genetika. Kaunas: Šviesa

Internet

2.

2011

Journal Trends in Genetics, Genetics, Trends in Plant Science, Plant Physiology, Plant Cell

 

Internet

3.

2008

A.J.F. Griffiths, S.R. Wessler, R.C. Lewontin, S.C. Carrol. An Introduction to Genetic Analysis. 8th ed. W.H. Freeman: NY

 

 

Course programme designed by

Prof.dr. Algimantas Paulauskas, Department of Biology, Faculty of Natural Sciences

Additional information