Klaida
  • Įvyko klaida įkeliant kanalų duomenys

General Biochemistry 1 (BBK 3005)

Course code

Course group

Volume in ECTS credits

Course hours

BBK 3005

C

6

160

Course type (compulsory or optional)

Compulsory

Course level (study cycle)

Bachelor

Semester the course is delivered

Autumn

Study form (face-to-face or distant)

Face-to-face

Course title in Lithuanian

BENDROJI BIOCHEMIJA I (Biomolekulės)

Course title in English

GENERAL BIOCHEMISTRY  I (Biomolecules)

Short course annotation in Lithuanian

Biochemijos I kurso tikslas suteikti studentui pagrindines žinias apie chemines medžiagas, kurios yra gyvųjų organizmų funkcionavimo pagrindas. Studentai įgis žinių apie pagrindinių cheminių junginių – baltymų, lipidų, sacharidų ir nukleorūščių – struktūrą fizines ir chemines savybes, bei funkcijas, apie fermentus ir fermentinės katalizės esmę, biologinių membranų struktūrą, medžiagų pernašos pro biologines membranas principus. Gautos žinios leis suprasti gyvųjų sistemų cheminės sandaros bei funkcionavimą, įgaus praktinio darbo su biomolekulėmis laboratorinius.

Short course annotation in English

The course introduces knowledge about structure and function of biomolecules: proteins, nucleic acids, carbohydrates and lipids. This course includes also basic knowledge on enzymes structure and biocatalysis, composition and functions of biomembranes, and principles of membrane transport. In practicals technical skills of biochemical methods are gained. Teaching methods are: lectures and laboratory works.

Prerequisites for entering the course

Neorganic chemistry, Organic chemistry

Course aim

The aim of course to introduce basic knowledge about chemical composition of living systems: proteins nucleic acids, carbohydrates, lipids.

Content (topics)

 1. Introduction to the chemistry of life.
 2. The role of water in biological process. The nature of noncovalent interactions.
 3. Amino acids.
 4. Proteins.
 5. Protein function: Myoglobin and hemoglobin.
 6. Carbohydrates oligosaccharide and  polysaccharides.
 7. Lipids.
 8. Nucleotides and nucleic acids.
 9. Naturally occurring organic nitrogen-containing bases – alkaloids.
 10. Enzymes.
 11. The kinetics of enzyme catalysis.
 12. Enzymes cofactors and coenzymes.
 13. Biological membranes.
 14. Complex molecules.
 15. Methods of protein purification and analyses.

Practical work (contents):

The course includes 10 practical works. 1) Reactions of amino acids. 2) Physical amd chemical properties of proteins. 3) Size Exclusion Chromatography. 4) Reactions of sacharides and lipides. 5) Quantitative evaluation of fructose amouont in fruits. 6) The influence of temperature on enzyme activity. 7)The influence of pH on enzyme activity. 8) Effect of the concentration of an enzyme on the rate of an enzyme catalyzed reaction. 9). Enzymes effectors. 10) Osmosis in potatoes.

Distribution of workload for students (contact and independent work hours)

Lectures – 45 hours, laboratory work– 30 hours,  mid-term and final examination – 7 hours, individual work – 80 hours.

Structure of cumulative score and value of its constituent parts

Final assessment sums the assessments of written final examination (50%), written mid-term examination (25%) and assessment of laboratory works (25%).

Recommended reference materials

No.

 

Publication year

Authors of publication and title

Publishing house

Number of copies in

University library

Self-study rooms

Other libraries 

Basic materials

1

2008

Kadziauskas J. Biochemija

VU leidykla

70

1

 

2

2003

A.Praškevičius, L.Ivanovienė, N.Stasiūnienė, J.Burneckienė, H.Rodovičius, L.Lukoševičius, D.Kondrotas. Biochemija

Printed KMU, Kaunas

22

 

 

3

1999

V.Mildažienė, J,Kadziauskas, R,Daugelavičius, V.Laurinavičius, Z.Naučienė, D.Bironaitė. Struktūrinė biochemija.

VDU

50

4

 

4

2000

D. Vieželienė, V. Mildažienė, Z. Naučienė, Biochemijos laboratoriniai darbai

Vytauto Didžiojo universitetas, Kaunas

50

3

 

Supplementary materials

1

2004

D.L. Nelson, M.M. Cox, A.T. Lehninger. Principles of biochemistry

Worth Publishers, N.Y.

 

2

2006

Donald Voet, Judith G. Voet. Fundamentals of Biochemistry, 2rd ed.

Printed in USA

 

Course programme designed by

Doc.dr. Zita Naučienė, Prof.habil.dr. Rimantas Daugelavičius, Department of Biochemistry and Biotechnology, Faculty of Natural Sciences

Additional information